It would be fantastic if he did
I don't have my hopes up though, its been close to a decade since he retired after all and he sadly isn't getting any younger. Still, there were some interesting hints on Robert Fripp's blog last year that Bowie was working on something with Eno. I have seen nothing more about this, but, and perhaps more telling, neither has it been denied yet (that I know of).
All hail the Lepper Messiah!